Non-Hodgkin lymphoma

Article

Non-Hodgkin lymphoma is a broad group of cancers arising from lymphocytes, the white blood cells involved in immune function. The group includes many distinct diseases with different cellular origins, genetic changes, growth rates, symptoms, and responses to treatment.

Most forms develop from B lymphocytes, while others arise from T cells or natural killer cells. Lymphoma may involve lymph nodes, bone marrow, spleen, blood, or organs outside the lymphatic system.

Symptoms can include enlarged lymph nodes, fever, night sweats, weight loss, fatigue, itching, or effects related to a particular organ. Diagnosis relies on tissue examination, immunophenotyping, imaging, laboratory testing, and often molecular or genetic analysis.

Classification separates indolent lymphomas, which may grow slowly, from aggressive forms that can progress rapidly. Treatment depends on the subtype and extent of disease and may include observation, immunotherapy, chemotherapy, targeted therapy, radiation, transplantation, or combinations of these.

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• Source / publisher: Wikipedia
• URL type: WWW
• Credits: Wikipedia
• URL: https://en.wikipedia.org/wiki/Non-Hodgkin_lymphoma